Igama lemveliso: IGuanidine Hydrochloride

Aminoformamidine hydrochloride okanye iGuanidinium chloride

Inkangeleko: yintlama emhlophe okanye emthubi.

Idatha yepropathi yomzimba

1. Uphawu: iqhuma elimhlophe okanye limthubi

2. Indawo yokunyibilika (℃): 181-183

3.Ubuninzi bezihlobo (g / ml, 20/4 ℃): 1.354

4.Unyibiliko: 228g kumanzi ayi-100g, i-76g kwi-100g methanol kunye ne-24g kwi-100g ethanol ngo-20 ℃. Phantse ungenakunyibilika kwi-acetone, i-benzene kunye ne-ether.

Ixabiso le-PH (4% isisombululo samanzi, 25 ℃): 6.4

Iipropathi kunye nozinzo

Le mveliso ayizinzanga kwaye inokufakwa i-hydrolyzed ibe yi-ammonia kunye ne-urea kwisisombululo esinamandla, ke ngoko ityhefu yayo iyafana naleyo ye-urea. IGuanidine kunye neziphumo zayo zihlala zinetyhefu kune-urea.

Injongo: 1. Ingasetyenziswa njengophakathi kunyango, isibulali zinambuzane, idayi kunye nolunye udibaniso lwezinto eziphilayo. Ingasetyenziselwa ukudibanisa i-2-Aminopyrimidine, 2-amino-6-methylpyrimidine kunye ne-2-amino-4,6-dimethylpyrimidine. Iphakathi ekuvelisweni kwesulfadiazine, sulfamethylpyrimidine kunye nesulfadimidine.

2. IGuanidine hydrochloride (okanye i-guanidine nitrate) iyadibana ne-ethyl cyanoacetate ukwenza i-2,4-diamino-6-hydroxypyrimidine, esetyenziselwa ukudibanisa iziyobisi ze-anemia folic acid. Ingasetyenziselwa njengearhente ye-antistatic yeentsinga zokwenziwa.

3. Isenokusetyenziswa njengeprotein denaturant.

1. Njenge-denaturant eyomeleleyo kuvavanyo lokufumana i-RNA iyonke. Isisombululo seGuanidine hydrochloride sinokunyibilikisa iprotheyini, kubangele ukonakala kwesakhiwo seseli, ukonakala kweprotein yenyukliya, ukwahlula kwi-acid ye-nucleic, ukongeza, i-RNase inokungasebenzi ngokunciphisa iarhente efana ne-guanidine hydrochloride.

indlela yokwenziwa

Sebenzisa i-dicyandiamide kunye ne-ammonium ityuwa (i-ammonium chloride) njengezinto ezingekenziwa, i-guanidine hydrochloride ekrwada yafunyanwa ngokunyibilika kwi-170-230 ℃, kwaye imveliso egqityiweyo yafunyanwa ngokucokiswa.

Ulawulo loqhagamshelwano

1. Musa ukungenisa uthuli

2. Inobungozi xa iginyiwe

3. Ukucaphuka kwamehlo

4. Ukucaphuka kolusu

Ukhuseleko lomntu

1. Nxiba impahla ekhuselayo ukunqanda ukudibana ngqo okanye ukuphefumla; 2. Musa ukusela, ungatyi okanye utshaye emsebenzini; 3. Sebenzisa iiglasi zokhuseleko